Volume 1

Editorial V1 N1

Editorials, Volume 1, Issue 1, Pages 1-54

The birth of a new journal is usually a cause for singular rejoicing and anticipation. On this occasion, however, the moment is steeped in melancholy with the recent passing of Professor Avijit Lahiri, the journal’s founder. He lived life to the full. Avijit touched countless friends and colleagues with his support, kindness and mentorship. At the same time, he was a pioneer in cardiodiabetes, an excellent clinician and an outstanding academic mind. In short, he was a trailblazer.

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Predictors for coronary artery calcium score and differences in its distributions between populations with and without diabetes

Original Articles, Volume 1, Issue 1, Pages 1-54

Background and aimsCoronary artery calcium (CAC) scoring is a method of measure coronary plaque burden and has been shown as an excellent predictor for atherosclerotic cardiovascular disease (ASCVD). Diabetes mellitus (DM) is an established risk factor for ASCVD, but a certain portion of patients with DM do not have CAC (score = 0). We conducted

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Prevention and Management of Heart Failure: Role of SGLT2 Inhibitors in Patients With and Without Diabetes

Original Articles, Volume 1, Issue 1, Pages 1-54

Certain antidiabetic therapies have adverse cardiovascular (CV) consequences. The recommendations for CV safety studies for new antidiabetic therapies led to the discovery that the sodium-glucose cotransporter-2 inhibitors (SGLT2is) have benefits in heart failure (HF) management. Mounting evidence from large, international, randomized, placebo-controlled trials have consistently demonstrated a reduction in hospitalizations for heart failure (HHF) among

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Cardiovascular Magnetic Resonance in Cardiomyopathy

Original Articles, Volume 1, Issue 1, Pages 1-54

Cardiomyopathies are defined as “myocardial disorders in which the heart muscle is structurally and functionally abnormal, in the absence of attributable coronary artery disease, hypertension, heart valve or congenital heart disease”. This is an aetiologically and clinically diverse group of conditions, sharing important characteristics such as risk of sudden cardiac death (SCD) and possible heritable

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Epidemiology of Cardiovascular Disease in Type 2 Diabetes Mellitus

Original Articles, Volume 1, Issue 1, Pages 1-54

Type 2 diabetes is a major and accelerating public health challenge. Type 2 diabetes is increasingly found to be a heterogeneous condition, where risk of cardiovascular disease that traditionally has been estimated at 2–4 times that of the nondiabetic population.Cardiovascular (CV) risk factors such as obesity, hypertension and dyslipidemia are common in patients with DM,

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Inflammation and Cardiometabolic Diseases: Lessons Learned From Psoriasis

Original Articles, Volume 1, Issue 1, Pages 1-54

Cardiometabolic disease encompasses a variety of metabolic dysfunctions including major public health issues such as insulin resistance, obesity, Type 2 Diabetes (T2DM), and cardiovascular disease (CVD). Inflammation drives the pathogenesis of cardiometabolic disease in clinical, epidemiological, and translational models. T2DM is an established inflammatory condition with many cardiometabolic relationships and is often associated with dyslipidemia

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Beware of the Travel-Sick Doctor!

Original Articles, Volume 1, Issue 1, Pages 1-54

An acute-onset, unilaterally fixed mydriasis can be a sign of life-threatening intracranial pathology e.g. intracranial bleed, but can also be due to more benign causes. We present a case of a healthy 46-year-old ICU nurse who developed an acute-onset unilateral mydriasis secondary to the accidental inoculation of her eye with hyoscine from a scopolamine patch she’d applied to a doctor for motion sickness. Due to the association of life-threatening intracranial pathology with a fixed mydriatic pupil, it is important to differentiate between pharmacologically-induced and pathological anisocoria. In this instance, the concern to exclude intracranial pathology can often lead to a plethora of unnecessary investigations and significant patient anxiety.

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